Next-generation sequencer capable of sequencing DNA much faster than earlier models (© Illumina).The National Cancer Center is using this device to create role models for treatment systems.The National Cancer Center Hospital—the main hub in Japan for conquering cancer.16Kuniko Sunami of the National Cancer Center, Japan, which is the leading Japanese institution in this field. At Japan’s National Cancer Center, several projects are underway to apply precision medicine to cancer, which continues to affect a growing number of people around the world. One of these, TOP-GEAR (Trial of Onco-Panel for Gene-profiling to Estimate both Adverse events and Response), which started in 2013, involves clinical research that uses a next-generation sequencer—a device that reads large amounts of genetic data at one time—with the goal of detecting cancer-related genes and structuring treatments on that basis. So far, about 100 cancer-related genes have been analyzed, and this data has been usefully linked to treatments pertaining to in approximately 15% of the patients. This means that the days of “cancer drug therapy” referred to cytotoxic chemotherapy are over, because now therapies such as molecularly-targeted therapy, which is highly genetic abnormalities FEATURE Seeds of SDGsn terms of being a super-aging society, Japan is ahead of the rest of the world. Facing problems that other nations will confront in the near future, Japan is promoting research into the latest medical technologies, with a goal “to achieve good health and longevity.” One such technology is precision medicine. “Genomic data from the tissue of individual patients are analyzed, and an appropriate treatment is selected based on any genetic abnormalities that are present,” explains Dr. In Japan, research into the new field of precision medicine is advancing, and a goal has been set “to achieve good health and longevity,” which is one of Japan’s priority areas for the achievement of Sustainable Development Goals (SDGs)Optimal Medical Treatment for EveryoneI
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